If an app on your Mac stops responding and you can’t quit the app normally, use Force Quit to close the app.
How to force an app to quit
Press these three keys together: Option, Command, and Esc (Escape). Or choose Force Quit from the Apple menu in the upper-left corner of your screen. (This is similar to pressing Control-Alt-Delete on a PC.)
Then select the app in the Force Quit window and click Force Quit.
You can even force the Finder to quit, if it stops responding: Select Finder in the Force Quit window, then click Relaunch.
Credit to Apple support.
From Apple Support website